Hypothyroidism after treatment with ketoconazole.

Hypothyroidism after treatment with Bamethasemol in Iran, Comparison of the Effect of Methimazole in Tehran and Boston

The response tomethimazole(l-methyl-2-mercaptoimidazol,MMl) therapy was evaluated in 18 patients with diffuse toxic goitre residing in an area of iodine deficiency(Tehran)and in 18 such patients residing in an area of iodine sufficiency(Boston) .Free T4 index(FT4I) decreased from 22.9± 4.8 to 4.9± 4.3 in Tehran and from 23.8± 5.2 to 17.0±4.1 in Boston, 4 weeks after administration of MMl 10 mg ...

Persistent nephrogenic diabetes insipidus, hyperparathyroidism, and hypothyroidism after lithium treatment.

Transient hypothyroidism after iodine-131 treatment for thyrotoxicosis.

Thirty consecutive patients with thyrotoxicosis were followed up at monthly intervals for 6 months after treatment with iodine-131. Serum total T4, serum total T3, and serum TSH response to TRH were measured at each review. Biochemical evidence of hypothyroidism (low T4 raised basal TSH) developed in 18 patients 1-4 months after treatment. In 5 of these patients, symptoms and signs of hypothyro...

Pseudotumor cerebri during Cushing's disease treatment with ketoconazole.

Benign intracranial hypertension (Pseudotumor cerebri) has been described as related to the reduction in steroid levels in Cushing's disease (CD), especially after surgical remission. Ketoconazole is a common and effective adjuvant therapy for hypercortisolism, but the major concern is liver enzyme dysfunction. We describe here the case of a 12-year old girl with CD who developed benign intracr...

Resolution of chronic severe refractory thrombocytopenia after treatment of hypothyroidism.

The case of a 52 year old woman with chronic severe refractory thrombocytopenia is presented. Over a three year period, her platelet count was persistently less than 20 x 10(9)/litre (normal range, 150-400). She required repeated hospital admission for management of bleeding and received multiple blood transfusions. She was given repeated courses of steroids, immunosuppression, immunoglobulin, ...